BRCA 1 & BRCA2 Test Price in Dubai | BRCA Gene Testing in Dubai | BRCA Test at Home

BRCA 1 & BRCA 2 Test & Purpose:

BRCA1 and BRCA2 are two different genes that produce proteins responsible for repairing damaged DNA. Mutations in these genes are associated with a higher risk of certain cancers, particularly breast and ovarian cancer. Here’s a breakdown of what you should know about BRCA1 and BRCA2:

BRCA1 vs. BRCA2

1. Gene Functions:

• BRCA1: Primarily involved in repairing DNA breaks and maintaining genomic stability. Mutations can increase the risk of breast, ovarian, and other cancers.
• BRCA2: Also involved in repairing DNA breaks, but it works differently from BRCA1. Mutations in BRCA2 can increase the risk of breast, ovarian, prostate, and pancreatic cancers.

2. Cancer Risks:

• BRCA1 Mutations: Women with BRCA1 mutations have a 55-65% lifetime risk of developing breast cancer and a 39% risk of developing ovarian cancer. Men with BRCA1 mutations have a slightly increased risk of breast cancer and other cancers.
• BRCA2 Mutations: Women with BRCA2 mutations have a 45-55% lifetime risk of breast cancer and a 11-17% risk of ovarian cancer. Men with BRCA2 mutations have an increased risk of breast cancer (though less common) and a higher risk of prostate and pancreatic cancers compared to those without the mutation.

3. Testing:

• Purpose: Genetic testing for BRCA1 and BRCA2 helps assess the risk of developing breast, ovarian, and other cancers. This is particularly relevant for individuals with a family history of these cancers.
• Range: Testing typically involves a blood or saliva sample analyzed for mutations in both BRCA1 and BRCA2 genes. The results can be either positive (indicating a mutation) or negative (indicating no detectable mutation). In some cases, results may be inconclusive or indicate variants of uncertain significance (VUS).

4. Management:

• Positive Test Results: If a BRCA1 or BRCA2 mutation is detected, individuals may discuss preventive measures with their healthcare provider, including increased surveillance, prophylactic surgeries (e.g., mastectomy, oophorectomy), or chemoprevention.
• Family Implications: Since BRCA mutations are hereditary, family members may also consider genetic testing to assess their risk.

Understanding the specific mutation and its implications can guide personalized prevention and treatment strategies. If you’re considering testing or have received results, consulting with a genetic counselor or specialist is crucial for interpreting the findings and planning next steps.

How much does a BRCA Test cost in Dubai?

BRCA Test Ranges between 2500-3500 Aed